The No. 11 Clemson Tigers (6-1) are heavy, 10.5-point favorites at home versus the Louisville Cardinals (5-3) on Saturday, November 2, 2024. Each team has a high-powered offense, with the Tigers fourth in points per game and the Cardinals 20th. The over/under in this outing is 63.5 points.

In this article, you will see the spread and odds across multiple sportsbooks for the Clemson vs. Louisville matchup.

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Clemson vs. Louisville Game Info

• Date: Saturday, November 2, 2024
• Time: 7:30 p.m. ET
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)
• City: Berkeley, California
• Venue: Memorial Stadium (Clemson, SC)

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Clemson vs. Louisville Odds, Spread, Over/Under

See the odds, spread and over/under for this matchup posted at different sportsbooks.

Make smart decisions. Use those stats when making your college football picks and place your bet on BetMGM.

Clemson vs. Louisville Betting Trends

• Clemson has compiled a 4-3-0 ATS record so far this year.
• The Tigers have covered the spread four times this season (4-2 ATS) when playing as at least 10.5-point favorites.
• Louisville has won two games against the spread this season.

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