Trying to find information on the best bets in ACC action in Week 4? Our computer model favors betting on the over/under in the North Carolina State vs. Clemson matchup, and picking Coastal Carolina (+3.5) over Virginia on the spread. You can find more insights and stats on those college football games, as well as potential options to parlay, by scrolling down.

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Best Week 4 ACC Spread Bets

Pick: Coastal Carolina +3.5 vs. Virginia

• Matchup: Virginia Cavaliers at Coastal Carolina Chanticleers
• Projected Winner & Margin of Victory: Coastal Carolina by 11.4 points
• Date/Time: Sept. 21 at 2:00 PM ET
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Pick: South Florida +16.5 vs. Miami (FL)

• Matchup: Miami (FL) Hurricanes at South Florida Bulls
• Projected Winner & Margin of Victory: Miami (FL) by 1.8 points
• Date/Time: Sept. 21 at 7:00 PM ET
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: North Carolina State +20.5 vs. Clemson

• Matchup: North Carolina State Wolfpack at Clemson Tigers
• Projected Winner & Margin of Victory: Clemson by 7.5 points
• Date/Time: Sept. 21 at 12:00 PM ET
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: James Madison +10.5 vs. North Carolina

• Matchup: James Madison Dukes at North Carolina Tar Heels
• Projected Winner & Margin of Victory: James Madison by 2.3 points
• Date/Time: Sept. 21 at 12:00 PM ET
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Middle Tennessee +14.5 vs. Duke

• Matchup: Duke Blue Devils at Middle Tennessee Blue Raiders
• Projected Winner & Margin of Victory: Duke by 7.1 points
• Date/Time: Sept. 21 at 4:00 PM ET
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Use these spread picks at BetMGM today!

Best Week 4 ACC Total Bets

Over 47 – North Carolina State vs. Clemson

• Matchup: North Carolina State Wolfpack at Clemson Tigers
• Projected Total: 58.5 points
• Date/Time: Sept. 21 at 12:00 PM ET
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 44.5 – California vs. Florida State

• Matchup: California Golden Bears at Florida State Seminoles
• Projected Total: 38.7 points
• Date/Time: Sept. 21 at 7:00 PM ET
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 47.5 – James Madison vs. North Carolina

• Matchup: James Madison Dukes at North Carolina Tar Heels
• Projected Total: 42 points
• Date/Time: Sept. 21 at 12:00 PM ET
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 58.5 – TCU vs. SMU

• Matchup: TCU Horned Frogs at SMU Mustangs
• Projected Total: 54 points
• Date/Time: Sept. 21 at 5:00 PM ET
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 45.5 – Michigan State vs. Boston College

• Matchup: Michigan State Spartans at Boston College Eagles
• Projected Total: 41.5 points
• Date/Time: Sept. 21 at 8:00 PM ET
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Take advantage of our picks and place your bet at BetMGM today!

Week 4 ACC Standings

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