There are several strong matchups on Saturday in ACC play, including the Notre Dame Fighting Irish taking on the Duke Blue Devils. If you’re looking for picks against the spread, continue reading.

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ACC Picks ATS Today

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Pick: Louisville +4.5 vs. Pittsburgh

• Matchup: Louisville Cardinals at Pittsburgh Panthers
• Projected Favorite & Spread: Pittsburgh by 4 points (Bet on BetMGM)
• Spread: Pittsburgh -4.5
• Time: 12:00 PM ET
• Date: January 11
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Duke -19.5 vs. Notre Dame

• Matchup: Notre Dame Fighting Irish at Duke Blue Devils
• Projected Favorite & Spread: Duke by 20.7 points (Bet on BetMGM)
• Spread: Duke -19.5
• Time: 12:00 PM ET
• Date: January 11
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Florida State +9.5 vs. Clemson

• Matchup: Florida State Seminoles at Clemson Tigers
• Projected Favorite & Spread: Clemson by 3.9 points (Bet on BetMGM)
• Spread: Clemson -9.5
• Time: 2:00 PM ET
• Date: January 11
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Syracuse +1 vs. Boston College

• Matchup: Syracuse Orange at Boston College Eagles
• Projected Favorite & Spread: Syracuse by 0.7 points (Bet on BetMGM)
• Spread: Boston College -1
• Time: 3:00 PM ET
• Date: January 11
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Georgia Tech +10 vs. SMU

• Matchup: Georgia Tech Yellow Jackets at SMU Mustangs
• Projected Favorite & Spread: SMU by 8 points (Bet on BetMGM)
• Spread: SMU -10
• Time: 4:00 PM ET
• Date: January 11
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Virginia +7.5 vs. Stanford

• Matchup: Virginia Cavaliers at Stanford Cardinal
• Projected Favorite & Spread: Stanford by 7.1 points (Bet on BetMGM)
• Spread: Stanford -7.5
• Time: 4:00 PM ET
• Date: January 11
• TV Channel: ESPNU
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: North Carolina -4.5 vs. NC State

• Matchup: North Carolina Tar Heels at NC State Wolfpack
• Projected Favorite & Spread: North Carolina by 7 points (Bet on BetMGM)
• Spread: North Carolina -4.5
• Time: 4:00 PM ET
• Date: January 11
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Miami (FL) +2.5 vs. Wake Forest

• Matchup: Wake Forest Demon Deacons at Miami Hurricanes
• Projected Favorite & Spread: Wake Forest by 1.5 points (Bet on BetMGM)
• Spread: Wake Forest -2.5
• Time: 5:15 PM ET
• Date: January 11
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Pick: Cal -6.5 vs. Virginia Tech

• Matchup: Virginia Tech Hokies at California Golden Bears
• Projected Favorite & Spread: Cal by 6.6 points (Bet on BetMGM)
• Spread: Cal -6.5
• Time: 6:00 PM ET
• Date: January 11
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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