According to our computer projection model, the No. 17 Clemson Tigers will beat the Pittsburgh Panthers when the two teams play at Acrisure Stadium on Saturday, Nov. 16, which kicks off at 12 p.m. ET. For our projections on the spead, point total, and final score, check out the rest of the article below.

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Clemson vs. Pittsburgh Predictions and Picks

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Clemson Betting Info (2024)

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• Based on this contest’s moneyline, the Tigers have an implied win probability of 79.1%.
• The Tigers have five wins in nine games against the spread this season.
• In games this season when favored by 10 points or more, Clemson are 4-3 against the spread.
• This season, three of the Tigers’ nine games have hit the over.
• The over/under in this matchup is 54 points, 0.2 fewer than the average total in this season’s Clemson contests.

Pittsburgh Betting Info (2024)

• The moneyline for this contest implies a 25.4% chance of a victory for the Panthers.
• The Panthers are 6-3-0 against the spread this season.
• The Panthers have hit the over in four of their nine games with a set total (44.4%).
• Pittsburgh games this year have averaged a total of 59.9 points, 5.9 more than the point total in this matchup.

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Tigers vs. Panthers 2024 Scoring Averages

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