If you are looking for information on the best bets in ACC play in Week 12, or creating a parlay bet, our computer model is here to help. It likes betting on the over/under in the Clemson vs. Pittsburgh matchup, and taking Pittsburgh (+10) over Clemson on the spread. You can find more stats and insights on those college football games by scrolling down.

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Best Week 12 ACC Spread Bets

Pick: Pittsburgh +10 vs. Clemson

• Matchup: Clemson Tigers at Pittsburgh Panthers
• Projected Winner & Margin of Victory: Clemson by 3.6 points
• Date/Time: Nov. 16 at 12:00 PM ET
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Louisville -20.5 vs. Stanford

• Matchup: Louisville Cardinals at Stanford Cardinal
• Projected Winner & Margin of Victory: Louisville by 25.3 points
• Date/Time: Nov. 16 at 3:30 PM ET
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: North Carolina -11 vs. Wake Forest

• Matchup: Wake Forest Demon Deacons at North Carolina Tar Heels
• Projected Winner & Margin of Victory: North Carolina by 15.3 points
• Date/Time: Nov. 16 at 8:00 PM ET
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Syracuse +8.5 vs. California

• Matchup: Syracuse Orange at California Golden Bears
• Projected Winner & Margin of Victory: California by 5.1 points
• Date/Time: Nov. 16 at 3:00 PM ET
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Notre Dame -22.5 vs. Virginia

• Matchup: Virginia Cavaliers at Notre Dame Fighting Irish
• Projected Winner & Margin of Victory: Notre Dame by 24.9 points
• Date/Time: Nov. 16 at 3:30 PM ET
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Use these spread picks at BetMGM today!

Best Week 12 ACC Total Bets

Over 53.5 – Clemson vs. Pittsburgh

• Matchup: Clemson Tigers at Pittsburgh Panthers
• Projected Total: 59.5 points
• Date/Time: Nov. 16 at 12:00 PM ET
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 63.5 – Wake Forest vs. North Carolina

• Matchup: Wake Forest Demon Deacons at North Carolina Tar Heels
• Projected Total: 61.1 points
• Date/Time: Nov. 16 at 8:00 PM ET
• TV Channel: ACC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 53.5 – Boston College vs. SMU

• Matchup: Boston College Eagles at SMU Mustangs
• Projected Total: 55.6 points
• Date/Time: Nov. 16 at 3:30 PM ET
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Over 50.5 – Virginia vs. Notre Dame

• Matchup: Virginia Cavaliers at Notre Dame Fighting Irish
• Projected Total: 51.4 points
• Date/Time: Nov. 16 at 3:30 PM ET
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Under 55.5 – Syracuse vs. California

• Matchup: Syracuse Orange at California Golden Bears
• Projected Total: 54.6 points
• Date/Time: Nov. 16 at 3:00 PM ET
• TV Channel: The CW
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Take advantage of our picks and place your bet at BetMGM today!

Week 12 ACC Standings

Watch ACC games all season long on Fubo and ESPN+!

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