The No. 11 Clemson Tigers (6-1) face an ACC matchup versus the Louisville Cardinals (5-3). For odds and best bets, keep scrolling.

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When and Where is Clemson vs. Louisville?

• Date: Saturday, November 2, 2024
• Time: 7:30 p.m. ET
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo
• City: Berkeley, California
• Venue: Memorial Stadium (Clemson, SC)

Clemson vs. Louisville Prediction & Moneyline Pick

• Prediction: Clemson 34, Louisville 29
• Clemson is -431 on the moneyline, and Louisville is +326.
• Clemson has been the moneyline favorite a total of six times this season, and they’ve won each of those games.
• The Tigers have won all six games they have played as a moneyline favorite with odds of -431 or shorter.
• Louisville has lost both games it has played as underdogs this season.
• The Cardinals have not been a bigger underdog this season than the +326 moneyline set for this game.
• The implied moneyline probability in this matchup gives the Tigers an 81.2% chance to win.

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Against the Spread Pick

• Pick ATS:

  Louisville (+10.5)
  

• In seven Clemson games this year, it has four wins against the spread.
• The Tigers have an against the spread record of 4-2 in their six games as a favorite of 10.5 points or more so far this season.
• Thus far in 2024 Louisville has two wins against the spread.

You can place your bet against the spread at BetMGM.

Best Over/Under Pick

• Pick OU: Under (63.5)
• This season, three of Clemson’s seven games have gone over Saturday’s total of 63.5 points.
• There has been just one game featuring Louisville this season with more combined scoring than Saturday’s total of 63.5.
• The over/under for the game of 63.5 is 15.1 points fewer than the combined points per game averages for Clemson (42 points per game) and Louisville (36.6 points per game).

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Key Stats Splits

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