There are 49 FBS matchups on the Week 6 card, with Auburn vs. Georgia among the best bets in terms of the total, based on our projections. For more tips, including parlay opportunities, see below.

Look for insights and computer predictions for that game and more below.

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College Football Computer Picks – Best Spread Bets

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Pick: Clemson +3.5 vs. Florida State

• Matchup: Clemson Tigers at Florida State Seminoles
• Projected Winner & Margin: Clemson by 14.4 points
• Time: 7:00 PM ET
• Date: Oct. 5
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Washington +8.5 vs. Michigan

• Matchup: Michigan Wolverines at Washington Huskies
• Projected Winner & Margin: Washington by 6.1 points
• Time: 7:30 PM ET
• Date: Oct. 5
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Georgia -23.5 vs. Auburn

• Matchup: Auburn Tigers at Georgia Bulldogs
• Projected Winner & Margin: Georgia by 36.1 points
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Missouri +4.5 vs. Texas A&M

• Matchup: Missouri Tigers at Texas A&M Aggies
• Projected Winner & Margin: Missouri by 3.2 points
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: ABC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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College Football Computer Picks – Best Total Bets

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